Multidetector computed tomography angiography for assessment of in-stent restenosis: meta-analysis of diagnostic performance

Table 6 Results for the bivariate logistic meta-regression on diagnostic performance: per stent analysis and detection of subgroups.

Covariable	Sensitivity (95%CI)	p value	Specificity (95%CI)	p value
Year of publication	0.84 [0.71–0.92]	0.64	0.93 [0.81–0.98]	0.72
No of detectors	0.82 [0.70–0.89]	0.97	0.88 [0.76–0.95]	0.57
Brand	0.74 [0.62–0.84]	0.29	0.93 [0.83–0.97]	0.74
Kernel	0.84 [0.73–0.90]	0.65	0.88 [0.76–0.94]	0.52
CTPCI	0.80 [0.69–0.88]	0.91	0.91 [0.82–0.96]	0.99
Strth	0.78 [0.69–0.85]	0.14	0.89 [0.79–0.94]	0.16
Exc	0.83 [0.67–0.93]	0.72	0.97 [0.93–0.98]	0.00
Location	0.00 [0.00–1.00]	1.00	0.89 [0.46–0.99]	0.82
Size	0.98 [0.62–1.00]	0.19	0.88 [0.24–0.99]	0.86
Age	0.79 [0.68–0.87]	0.84	0.93 [0.86–0.97]	0.74
Kv	0.81 [0.72–0.88]	0.91	0.92 [0.85–0.96]	0.85

If p-value is below 0.05 significant subgroups exist attributable to the investigated covariable. Sensitivity and specificity is given for the most deviating stratum with p-value comparing the values with the complete group without stratification. Only one covariable results in significant difference between strata: specificity is significantly different when grouping studies that excluded or included non-assessable segments. See also table 6 that compares some stratum specific sensitivities and specificities.
Legend for covariables see table 3
95% CI: 95% Confidence intervals

ISSN: 1471-2342