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Figure 8 | BMC Medical Imaging

Figure 8

From: Computer-assisted assessment of the Human Epidermal Growth Factor Receptor 2 immunohistochemical assay in imaged histologic sections using a membrane isolation algorithm and quantitative analysis of positive controls

Figure 8

ROC curves based solely on equivocal 2+ cases for three scoring methods: M a , M n , and Manual Scoring. The two left most arrows indicate significant decreases in false positive rate when using computer-assisted image analysis techniques. This may potentially show promise in reducing those patients who would otherwise be needlessly exposed to treatment toxicity. The reduction may be attributed to not only the features used, but also the greater ability of computer-assisted analysis to differentiate more than just one cutoff point in the 2+ equivocal range.

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BMC Medical Imaging

ISSN: 1471-2342

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