Figure 4
From: In vivo study of experimental pneumococcal meningitis using magnetic resonance imaging
Disease evolution visualized using MRI. Pre- and post contrast T1W images (a, b), T2W (c) images together with equivalent Histological slices (d) illustrate the evolution of the disease. Postcontrast T1W images were used to identify meningeal enhancement. Meningeal enhancement could be visually graded as (from left to right): 0) No enhancement, 1) Thin brim of enhancement, 2) Thick brim of enhancement and 3) Diffuse enhancement with unclear borders towards outer cortex layer. T2W images (c) clearly show increasing ventricular size that was also apparent in the histological slices.