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Table 1 Distribution and clinical features of soft tissue metastasis of 9 included patients

From: Prevalence and patterns of soft tissue metastasis: detection with true whole-body F-18 FDG PET/CT

Patient no.

Gender; age (y)

Cancer type; initial staging

Location, size/grading of primary lesion

Inside LWB – Sq

Outside LWB – Sq

Inside LWB – Sm

Outside LWB – Sm

Months from initial Dx to Dx of STM

Months of survival

Type of follow-up

1

M; 35

Melanoma; III

Left scalp, 4.3 mm

1: lt post-auricular*

0

0

0

3

DOD, 25

B

2

M; 71

Melanoma; III

Left upper arm, size n/a

10: lt shoulder, abdomen, back, pelvis, lt thigh

2: lt elbow, lt thigh

2: rt shoulder, rt thigh

7: rt thigh, lt thigh, lt lower leg

48

DOD, 56

B

3

M; 70

Melanoma, spindle type; IV

Right anterior chest, 1.4 mm

1: lt face

1: lt parietal skin

0

0

48

DOD, 53

B

4

M; 76

Melanoma; III

Right thigh, 4.8 mm

0

1: rt thigh*

0

0

4

DOD, 7

B

5

F; 65

Lung cancer, squamous ; IV

Left lung, 5.5 cm

0

0

1: rt paraspinal

0

6

DOD, 7

C

6

M; 44

Lung cancer, non-small cell with squamoid features; IV

Left lung, 3.8 cm

0

1: lt thigh

2: rt shoulder, lt thigh

0

1

DOD, 9

C

7

F; 64

Lymphoma, follicular cell; IV

Widespread tumor, grade II/III

1: rt chest

0

0

0

1

NED, 29

P

8

F; 56

Lymphoma, diffuse large B-cell, anaplastic variant; II

Left groin 5.1 cm; retroperitoneum, 4.5 cm

0

1: rt elbow

1: rt thigh

3: rt thigh, lt thigh

7

n/a

C

9

M; 63

Esophagealcancer, adenocarcinoma; staging n/a

Size n/a

0

0

3: lt arm, lt pelvis

3: lt thigh, rt calf, lt calf

12

DOD, 13

C

   

Total lesion number

13

6

9

13

   
   

SUVmax

5.5 ± 2.8 (1.5 – 9.6); all higher than liver uptake

8.9 ± 12.6 (1.0 – 37); 3/6 higher than liver uptake

5.8 ± 3.0 (2.2 – 10); all higher than liver uptake

3.4 ± 2.5 (0.9 – 8.4); 11/13 higher than liver uptake

   
   

CT appearance

13/13 hyperdense

6/6 hyperdense

4/9 isodense, 5/9 hypodense

8/13 isodense, 5/13 hypodense

   
   

Lesion size

8/13, < 1.5 cm; 5/13, 1.5 – 1.8 cm

4/6, < 1.5 cm; 2/6, 1.5 – 1.8 cm

1/9, < 1.5 cm; 8/9, 2.5 – 2.8 cm

7/13, < 1.5 cm; 6/13, 1.5 – 9 cm

   
  1. LWB, limited whole body; Sq, subcutaneous; Sm, skeletal muscle; rt, right; lt, left; NSCLC, non-small cell lung cancer; DOD, death of disease; NED, no evidence of disease; n/a, not available; STM, soft tissue metastasis; B, biopsy; C, clinical; P, PET/CT
  2. * in-transit metastasis; Breslow's depth