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Table 1 Distribution and clinical features of soft tissue metastasis of 9 included patients

From: Prevalence and patterns of soft tissue metastasis: detection with true whole-body F-18 FDG PET/CT

Patient no. Gender; age (y) Cancer type; initial staging Location, size/grading of primary lesion Inside LWB – Sq Outside LWB – Sq Inside LWB – Sm Outside LWB – Sm Months from initial Dx to Dx of STM Months of survival Type of follow-up
1 M; 35 Melanoma; III Left scalp, 4.3 mm 1: lt post-auricular* 0 0 0 3 DOD, 25 B
2 M; 71 Melanoma; III Left upper arm, size n/a 10: lt shoulder, abdomen, back, pelvis, lt thigh 2: lt elbow, lt thigh 2: rt shoulder, rt thigh 7: rt thigh, lt thigh, lt lower leg 48 DOD, 56 B
3 M; 70 Melanoma, spindle type; IV Right anterior chest, 1.4 mm 1: lt face 1: lt parietal skin 0 0 48 DOD, 53 B
4 M; 76 Melanoma; III Right thigh, 4.8 mm 0 1: rt thigh* 0 0 4 DOD, 7 B
5 F; 65 Lung cancer, squamous ; IV Left lung, 5.5 cm 0 0 1: rt paraspinal 0 6 DOD, 7 C
6 M; 44 Lung cancer, non-small cell with squamoid features; IV Left lung, 3.8 cm 0 1: lt thigh 2: rt shoulder, lt thigh 0 1 DOD, 9 C
7 F; 64 Lymphoma, follicular cell; IV Widespread tumor, grade II/III 1: rt chest 0 0 0 1 NED, 29 P
8 F; 56 Lymphoma, diffuse large B-cell, anaplastic variant; II Left groin 5.1 cm; retroperitoneum, 4.5 cm 0 1: rt elbow 1: rt thigh 3: rt thigh, lt thigh 7 n/a C
9 M; 63 Esophagealcancer, adenocarcinoma; staging n/a Size n/a 0 0 3: lt arm, lt pelvis 3: lt thigh, rt calf, lt calf 12 DOD, 13 C
    Total lesion number 13 6 9 13    
    SUVmax 5.5 ± 2.8 (1.5 – 9.6); all higher than liver uptake 8.9 ± 12.6 (1.0 – 37); 3/6 higher than liver uptake 5.8 ± 3.0 (2.2 – 10); all higher than liver uptake 3.4 ± 2.5 (0.9 – 8.4); 11/13 higher than liver uptake    
    CT appearance 13/13 hyperdense 6/6 hyperdense 4/9 isodense, 5/9 hypodense 8/13 isodense, 5/13 hypodense    
    Lesion size 8/13, < 1.5 cm; 5/13, 1.5 – 1.8 cm 4/6, < 1.5 cm; 2/6, 1.5 – 1.8 cm 1/9, < 1.5 cm; 8/9, 2.5 – 2.8 cm 7/13, < 1.5 cm; 6/13, 1.5 – 9 cm    
  1. LWB, limited whole body; Sq, subcutaneous; Sm, skeletal muscle; rt, right; lt, left; NSCLC, non-small cell lung cancer; DOD, death of disease; NED, no evidence of disease; n/a, not available; STM, soft tissue metastasis; B, biopsy; C, clinical; P, PET/CT
  2. * in-transit metastasis; Breslow's depth