Skip to main content

Table 2 The 25 included studies

From: MRCP compared to diagnostic ERCP for diagnosis when biliary obstruction is suspected: a systematic review

Study Total number Of patients Suspected Condition True +ve False +ve False -ve True -ve N Sensitivity (95% CI) Specificity (95% CI) Likelihood ratio-positive (95% CI) Likelihood ratio-negative (95% CI)*
Adamek[9] 86 Abnormality 42 1 5 12 60 0.89 (0.77, 0.95) 0.92 (0.67, 0.99) 11.62 (1.76, 76.57) 0.12 (0.02, 0.76)
Adamek 81 Malignancy 22 0 5 33 60 0.81 (0.63, 0.92) 1.00 (0.90, 1.00) 54.64 (3.47, 861.18) 0.20 (0.01, 3.14)
Angulo[11] 73 Normal 19 2 3 46 70 0.86 (0.67, 0.95) 0.96 (0.86, 0.99) 20.73 (5.28, 81.31) 0.14 (0.04, 0.56)
Angulo 70 dilitation CBD 38 2 3 27 70 0.93 (0.81, 0.97) 0.93 (0.78, 0.98) 13.44 (3.52, 51.33) 0.08 (0.02, 0.30)
Angulo 72 Obstruction 37 3 0 39 79 1.00 (0.91, 1.00) 0.91 (0.76, 0.97) 11.00 (3.74, 32.36) 0.00
Angulo 70 Choledocholithiasis 5 1 5 59 70 0.50 (0.24, 0.76) 0.98 (0.91, 1.00) 30.00 (3.90, 230.73) 0.51 (0.07, 3.91)
Angulo 70 PSC 19 1 4 46 70 0.83 (0.63, 0.93) 0.98 (0.89, 1.00) 38.83 (5.53, 272.37) 0.18 (0.03, 1.25)
Barish[12] 29 Dilitation 13 0 2 6 21 0.87 (0.62, 0.96) 1.00 (0.61, 1.00) 11.81 (0.81, 172.17) 0.17 (0.01, 2.45)
Calvo[13] 61 Choledocholithiasis 29 2 3 10 44 0.91 (0.76, 0.97) 0.83 (0.55, 0.95) 5.44 (1.53, 19.36) 0.11 (0.03, 0.40)
Chan[14] 47 Choledocholithiasis 18 4 1 22 45 0.95 (0.75, 0.99) 0.85 (0.66, 0.94) 6.16 (2.48, 15.26) 0.06 (0.03, 0.15)
Demartines[15] 40 Choledocholithiasis 19 2 0 19 40 1.00 (0.83, 1.00) 0.90 (0.71, 0.97) 10.50 (2.81, 39.24) 0.00
Dwerryhouse[16] 40 Choledocholithiasis 7 2 1 28 38 0.88 (0.53, 0.98) 0.93 (0.79, 0.98) 13.13 (3.35, 51.36) 0.1 (0.03, 0.52)
Guibaud[18] 79 Obstruction 72 0 7 47 126 0.91 (0.83, 0.96) 1.00 (0.92, 1.00) 87.00 (5.52, 1372.23) 0.09 (0.01, 1.49)
Guibaud   Choledocholithiasis 26 2 6 92 126 0.81 (0.65, 0.91) 0.98 (0.93, 0.99) 38.19 (9.60, 151.97) 0.19 (0.05, 0.76)
Guibaud   Malignancy 12 2 2 110 126 0.86 (0.60, 0.96) 0.98 (0.94, 1.00) 48.00 (11.96, 192.72) 0.15 (0.04, 0.58)
Holzknecht[20] 61 Choledocholithiasis 12 3 2 46 63 0.86 (0.60, 0.96) 0.94 (0.83, 0.98) 14.00 (4.58, 42.78) 0.15 (0.05, 0.47)
Holzknecht   Dilatation 32 2 2 26 62 0.94 (0.81, 0.98) 0.93 (0.77, 0.98) 13.18 (3.46, 50.23) 0.06 (0.02, 0.24)
Holzknecht   Stenosis 31 3 5 22 61 0.86 (0.71, 0.94) 0.88 (0.70, 0.96) 7.18 (2.46, 20.91) 0.16 (0.05, 0.46)
Holzknecht   Overall 43 3 4 12 62 0.91 (0.80, 0.97) 0.80 (0.55, 0.93) 4.57 (1.66, 12.63) 0.11 (0.04, 0.29)
Laokpessi[21] 101 Choledocholithiasis 105 0 8 34 147 0.93 (0.87, 0.96) 1.00 (0.90, 1.00) 64.78 (4.13, 1015.86) 0.08 (0.00, 1.19)
Lee[22] 46 Malignancy 17 2 4 23 46 0.81 (0.60, 0.92) 0.92 (0.75, 0.98) 10.12 (2.64, 38.86) 0.21 (0.05, 0.79)
Lomanto[23] 136 Choledocholithiasis 22 0 2 38 62 0.92 (0.74, 0.98) 1.00 (0.91, 1.00) 70.20 (4.46, 1105.97) 0.10 (0.01, 1.60)
Lomas[24] 76 Choledocholithiasis 9 2 0 58 69 1.00 (0.70, 1.00) 0.97 (0.89, 0.99) 30.00 (7.68, 117.19) 0.00
Lomas   Stricture 19 1 0 49 69 1.00 (0.83, 1.00) 0.98 (0.90, 1.00) 50.00 (7.18, 348.04) 0.00
Macaulay[25] 29 Dilatation 18 1 0 10 29 1.00 (0.82, 1.00) 0.91 (0.62, 0.98) 11.00 (1.70, 71.28) 0.00
Regan[26] 23 Choledocholithiasis 14 1 1 7 23 0.93 (0.70, 0.99) 0.88 (0.53, 0.98) 7.47 (1.19, 46.94) 0.08 (0.01, 0.48)
Reinhold[27] 110 Obstruction 69 0 7 34 110 0.91 (0.82, 0.95) 1.00 (0.90, 1.00) 63.18 (4.03, 991.27) 0.10 (0.01, 1.55)
Reinhold   Choledocholithiasis 27 3 3 77 110 0.90 (0.74, 0.97) 0.96 (0.90, 0.99) 24.00 (7.86, 73.31) 0.10 (0.03, 0.32)
Soto 1996[28] 46 Dilatation 26 1 1 16 44 0.96 (0.82, 0.99) 0.94 (0.73, 0.99) 16.37 (2.44, 109.77) 0.04 (0.01, 0.26)
Soto 2000[29] 57 Choledocholithiasis 23 1 1 24 49 0.96 (0.80, 0.99) 0.96 (0.80, 0.99) 23.96 (3.50, 163.78) 0.04 (0.01, 0.30)
Soto 2000[30] 51 Choledocholithiasis 25 0 1 25 51 0.96 (0.81, 0.99) 1.00 (0.87, 1.00) 49.11 (3.15, 765.62) 0.06 (0.00, 0.88)
Stiris[31] 50 Choledocholithiasis 28 1 4 17 50 0.88 (0.72, 0.95) 0.94 (0.74, 0.99) 15.75 (2.33, 106.28) 0.13 (0.02, 0.89)
Sugiyama[32] 159 anamalous PBJ 9 0 2 148 159 0.82 (0.52, 0.95) 1.00 (0.97, 1.00) 235.92 (14.60, 3811.82) 0.21 (0.01, 3.38)
Taylor[33] 146 Choledocholithiasis 45 9 1 74 129 0.98 (0.89, 1.00) 0.89 (0.81, 0.94) 9.02 (4.86, 16.74) 0.02 (0.01, 0.05)
Taylor   Stricture 12 1 0 118 131 1.00 (0.76, 1.00) 0.99 (0.95, 1.00) 118.00 (16.76, 830.78) 0.00
Textor[34] 150 PSC 29 1 4 108 142 0.88 (0.73, 0.95) 0.99 (0.95, 1.00) 95.79 (13.56, 676.70) 0.12 (0.02, 0.86)
Varghese[35] 191 Choledocholithiasis 31 3 3 154 191 0.91 (0.77, 0.97) 0.98 (0.95, 0.99) 47.72 (15.48, 147.06) 0.09 (0.03, 0.28)
Zidi[36] 70 Choledocholithiasis 28 0 21 21 70 0.57 (0.43, 0.70) 1.00 (0.85, 1.00) 25.08 (1.60, 392.61) 0.44 (0.03, 6.89)
  1. * With likelihood ratios of zero, the data are unsuitable for the calculation of 95% confidence intervals.