Table 1 Characteristics of FPLD patients compared to controls
| Â | GL2784 | GL2990 | GL0658 | GL0096 |
|---|---|---|---|---|
Diagnosis | Control | Control | FPLD3 | FPLD2 |
Mutation | Wild-type | Wild-type | PPARG F388L | LMNA R482Q |
Age (years) | 24 | 50 | 49 | 63 |
Sex | Female | Female | Female | Female |
Height (m) | 1.63 | 1.60 | 1.52 | 1.53 |
Weight (kg) | 61.7 | 89.1 | 80.2 | 58.1 |
Body mass index (kg/m2) | 23.5 | 34.8 | 33.4 | 24.8 |
Waist circumference (cm) | 78.8 | 103.6 | 105.7 | 88.3 |
Waist-to-hip circumference ratio | 0.88 | 0.86 | 0.88 | 0.92 |
Blood pressure (mmHg) | 113/63 | 154/89 | 138/88 (treated) | 131/76 (treated) |
BIA measures (PBF, %) | Â | Â | Â | Â |
   total body | 28.0 ± 0.2 | 47.5 ± 0.2 | 31.8 ± 0.2 | 29.7 ± 0.1 |
   right leg | 31.4 ± 0.1 | 49.5 ± 0.1 | 44.0 ± 0.2 | 36.8 ± 0.1 |
   left leg | 31.3 ± 0.1 | 49.2 ± 0.1 | 47.9 ± 0.5 | 37.7 ± 0.1 |
Mean sc+inf volume/slice (%) | Â | Â | Â | Â |
   mid-calf | 26.3 ± 1.1 | 34.8 ± 1.5 | 19.2 ± 1.7 | N/A |
   mid-thigh | 44.3 ± 2.1 | 56.1 ± 1.5 | 34.4 ± 2.5 | 24.3 ± 3.7 |
Overall sc+inf volume (%) | Â | Â | Â | Â |
   mid-calf | 26.2 | 34.7 | 19.2 | N/A |
   mid-thigh | 44.5 | 56.1 | 34.5 | 24.5 |