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Figure 4 | BMC Medical Imaging

Figure 4

From: Diffusion-weighted MRI characteristics of the cerebral metastasis to brain boundary predicts patient outcomes

Figure 4

ADC of the metastasis predicts subsequent patient outcomes. Cases such as that in A. an enhancing lesion with hypo-intense DWI signal and higher than median ADC were compared to those such as B. an enhancing lesion but with hyper-intense DWI signal and corresponding low readings on ADC map. C. The largest group of metastases (n = 36) from a single primary - lung non-small cell carcinoma – were stratified into two groups by these readings of tumor ADC. Overall survival was significantly longer for cases with a high tumor ADCmean (10.5 months, CI 7.7 – 13.2) versus a low tumor ADCmean (5.8 months, CI 3.2 – 8.4, Log rank = 4.135, p = 0.042). D. For the 66 cases where gross total resection was performed, local recurrence in the brain occurred in 16. Metastases with a higher ADC showed significantly longer progression free survival, 18.4 months (95% CI 11.6 – 25.1) versus 11.3 months (95% 5.8 – 16.8) in those with a low ADCmean (Log rank test, Chi Square 4.263, p = 0.039).

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