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Table 3 DWI cut-off values and performance values of tumor ADC, ADC-CR, and ADC-PR in predicting Gleason 8 and 9

From: Evaluation of the normal-to-diseased apparent diffusion coefficient ratio as an indicator of prostate cancer aggressiveness

 

Tumor ADC

ADC-CR

ADC-PR

Cut-off

≤ 0.82

≤ 0.57

≤ 0.5

Sensitivity

72.7

82.2

88.9

Specificity

70.6

66.7

64.7

AUROC

0.75

0.77

0.84

p value

< 0.001

< 0.001

< 0.001

  1. Note: AUC: area under the receiver operating characteristic curve. ADC-CR: ratio between tumor ADCs and healthy central gland tissue ADCs. ADC-PR: ratio between tumor ADCs and healthy peripheral zone tissue ADCs.