Figure 2
Placement of regions of interest (ROI) for (A) peripheral gland tumor (B) central gland tumor. A. Placement of regions of interest (ROI) for signal intensity measurements of Gleason 8 (4 + 4) peripheral tumor (white ROI = 0.78 × 10-3 mm2/s) and normal peripheral zone (black ROI = 1.9 × 10-3 mm2/s). The ADC-PR (white ROI/black ROI) is 0.41, which indicates a high-grade tumor. B. The white ROI is placed in the central gland (CG) portion of a Gleason 9 (4 + 5) lesion (0.82 × 10-3 mm2/s) while the black ROI is located in tumor-free CG tissue (1.87 × 10-3 mm2/s) The ADC-CR (white ROI/black ROI) is 0.43, which indicates a high-grade prostate tumor.