Flowchart of patients and lesions included in this trial. 194 patients underwent Gd-EOB-DTPA-enhanced MRI of the liver. 110 patients were excluded, mainly because of missing follow-up examinations, and 84 consecutive patients were included. Malignant lesions (n = 64) were proven by histology (n = 45), or diagnosis was either based on AFP > 196 ng/ml (n = 5) or knowledge of the primary tumor in case of metastases (n = 14). Benign lesions (n = 20) showed no change on follow-up examinations for more than 6 months.