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Table 2 Histological measurements: Mean ± SD

From: Tracking of In-111-labeled human umbilical tissue-derived cells (hUTC) in a rat model of cerebral ischemia using SPECT imaging

Conditions

In-111-oxine

In-111 labeled hUTC

% Lesion volume (a)

27.61±14.56 (10)

26.68±15.19 (11)

vWF+ vessels/mm2 (b)

200.45±43.05 (10)

243.90±43.45 (11)*

% Synaptophysin+ area (c)

11.26±1.31 (10)

14.36±4.30 (11)*

TUNEL+ cells/mm2 (d)

35.55±18.08 (10)

20.37±11.55 (11)

  1. N = number of rats/group is indicated in the brackets.
  2. (a) Lesion volume is expressed as a percent compared to the contralateral intact section of the brain.
  3. (b) von Willebrand factor (vWF) is a marker for blood vessels. Density of vWF vessels in IBZ (vessels/mm2).
  4. (c) Synaptophysin, a marker of synapses, is expressed as a percent area in the IBZ.
  5. (d) Apoptosis is expressed as the number of apoptotic cells per mm2.
  6. Asterisk indicates a significant difference.