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Table 3 The intra-observer repeatability and variability (N = 30) for FA and ADC (10- 3 mm2/s) (N = 30)

From: Repeatability and variation of region-of-interest methods using quantitative diffusion tensor MR imaging of the brain

  

Circular ROI

Freehand ROI

     

Mean diff. ± 2sd

   

Mean diff. ± 2sd

Region

Parameter

ICC

p

CV (%)

 

ICC

p

CV (%)

 

Basal pons

FA

0.74

< 0.001*

10.4

0.020 ± 0.093

0.63

< 0.001*

9.5

−0.061 ± 0.085

 

ADC

0.83

< 0.001*

7.9

−0.010 ± 0.038

0.70

0.001*

6.0

0.004 ± 0.082

Cerebral peduncle

FA

0.74

< 0.001*

5.9

0.006 ± 0.092

0.42

0.025

5.6

−0.038 ± 0.101

 

ADC

0.19

0.297

7.6

0.001 ± 0.145

0.29

0.141

6.1

0.030 ± 0.120

Internal capsule, post

FA

0.90

< 0.001*

5.5

−0.002 ± 0.049

0.66

< 0.001*

5.7

−0.043 ± 0.051

 

ADC

0.76

< 0.001*

3.5

0.006 ± 0.042

0.78

< 0.001*

2.3

−0.002 ± 0.027

Corona radiata

FA

0.84

< 0.001*

10.2

0.005 ± 0.077

0.86

< 0.001*

9.2

−0.013 ± 0.063

 

ADC

0.76

< 0.001*

4.2

−0.004 ± 0.048

0.86

< 0.001*

3.6

0.008 ± 0.030

Centrum semiovale

FA

0.48

0.041

13.1

−0.001 ± 0.160

0.26

0.121

9.5

−0.051 ± 0.128

 

ADC

0.63

0.005

5.5

−0.005 ± 0.079

0.87

< 0.001*

3.1

0.005 ± 0.028

Uncinate fasciculus

FA

0.67

0.002*

10.7

0.007 ± 0.116

0.61

< 0.001*

7.6

−0.051 ± 0.051

 

ADC

0.69

0.001*

4.1

0.000 ± 0.063

0.92

< 0.001*

3.7

−0.003 ± 0.031

Forceps minor

FA

0.76

< 0.001*

12.2

−0.009 ± 0.118

0.65

< 0.001*

9.1

−0.044 ± 0.067

 

ADC

0.64

0.005

4.6

−0.001 ± 0.073

0.89

< 0.001*

3.7

0.001 ± 0.035

Ant corona radiata

FA

0.71

0.001*

12.8

0.009 ± 0.133

0.61

< 0.001*

8.3

−0.036 ± 0.073

 

ADC

0.27

0.169

3.7

−0.017 ± 0.071

0.85

< 0.001*

3.7

−0.002 ± 0.040

CC genu

FA

0.67

0.002*

4.7

0.008 ± 0.078

0.15

0.002*

5.7

−0.137 ± 0.082

 

ADC

0.93

< 0.001*

7.7

−0.008 ± 0.062

0.37

0.001*

6.5

0.089 ± 0.102

CC body

FA

0.23

0.203

5.8

0.027 ± 0.112

0.59

< 0.001*

9.0

−0.067 ± 0.091

 

ADC

0.26

0.107

9.8

−0.085 ± 0.195

0.50

0.002*

9.8

0.087 ± 0.166

CC splenium

FA

0.89

< 0.001*

6.1

0.002 ± 0.066

0.27

0.006

6.0

−0.094 ± 0.100

 

ADC

0.82

< 0.001*

6.6

−0.001 ± 0.075

0.34

0.015

5.9

0.060 ± 0.099

  1. ICC = intra-class correlation coefficient; CV = coefficient of variation; Mean diff. ± 2sd = 95% limits of agreement, * = the statistical significance p < 0.05/11 with Bonferroni correction for 11 regions.
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BMC Medical Imaging

ISSN: 1471-2342

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