|  | Circular ROI | Freehand ROI | ||||||
---|---|---|---|---|---|---|---|---|---|
Region | Parameter | Mean ± SD | ICC | p | CV(%) | Mean ± SD | ICC | p | CV(%) |
Basal pons | FA | 0.705 ± 0.044 | 0.44 | 0.004* | 8.6 | 0.621 ± 0.061 | 0.73 | < 0.001* | 9.2 |
 | ADC | 0.726 ± 0.069 | 0.24 | 0.226 | 8.9 | 0.730 ± 0.080 | 0.01 | 0.487 | 8.4 |
Cerebral peduncle | FA | 0.850 ± 0.035 | 0.62 | 0.006 | 4.9 | 0.788 ± 0.062 | 0.14 | 0.319 | 6.4 |
 | ADC | 0.706 ± 0.048 | 0.56 | 0.018 | 7.0 | 0.772 ± 0.070 | 0.49 | 0.008 | 6.8 |
Internal capsule, post | FA | 0.767 ± 0.046 | 0.67 | < 0.001* | 5.6 | 0.728 ± 0.036 | 0.80 | < 0.001* | 5.0 |
 | ADC | 0.696 ± 0.034 | 0.63 | 0.001* | 4.2 | 0.693 ± 0.021 | 0.84 | < 0.001* | 2.8 |
Corona radiata | FA | 0.508 ± 0.038 | 0.54 | 0.023 | 8.6 | 0.515 ± 0.047 | 0.78 | < 0.001* | 9.0 |
 | ADC | 0.648 ± 0.030 | 0.64 | 0.005 | 4.5 | 0.665 ± 0.025 | 0.93 | < 0.001* | 3.6 |
Centrum semiovale | FA | 0.501 ± 0.067 | 0.64 | 0.004* | 14.5 | 0.509 ± 0.051 | 0.47 | 0.007 | 9.9 |
 | ADC | 0.700 ± 0.042 | 0.75 | < 0.001* | 6.0 | 0.693 ± 0.024 | 0.86 | < 0.001* | 3.3 |
Uncinate fasciculus | FA | 0.529 ± 0.060 | 0.62 | 0.007 | 11.7 | 0.517 ± 0.050 | 0.74 | < 0.001* | 8.5 |
 | ADC | 0.779 ± 0.036 | 0.55 | 0.018 | 4.4 | 0.768 ± 0.025 | 0.84 | < 0.001* | 3.7 |
Forceps minor | FA | 0.545 ± 0.057 | 0.64 | 0.004* | 12.0 | 0.499 ± 0.051 | 0.83 | < 0.001* | 9.5 |
 | ADC | 0.762 ± 0.046 | 0.17 | 0.319 | 5.1 | 0.757 ± 0.029 | 0.88 | < 0.001* | 3.7 |
Ant corona radiata | FA | 0.551 ± 0.073 | 0.84 | < 0.001* | 13.7 | 0.497 ± 0.040 | 0.86 | < 0.001* | 8.3 |
 | ADC | 0.754 ± 0.029 | 0.45 | 0.060 | 3.8 | 0.748 ± 0.024 | 0.82 | < 0.001* | 3.5 |
CC genu | FA | 0.836 ± 0.034 | 0.80 | < 0.001* | 4.2 | 0.785 ± 0.051 | 0.51 | 0.013 | 5.3 |
 | ADC | 0.765 ± 0.044 | 0.80 | < 0.001* | 6.2 | 0.846 ± 0.069 | 0.37 | 0.012 | 7.3 |
CC body | FA | 0.696 ± 0.057 | 0.39 | 0.066 | 6.7 | 0.654 ± 0.069 | 0.62 | 0.003* | 9.8 |
 | ADC | 0.821 ± 0.164 | 0.61 | 0.008 | 15 | 0.862 ± 0.114 | 0.65 | 0.001* | 12.2 |
CC splenium | FA | 0.864 ± 0.047 | 0.90 | < 0.001* | 5.6 | 0.838 ± 0.043 | 0.88 | < 0.001* | 5.2 |
 | ADC | 0.717 ± 0.038 | 0.81 | < 0.001* | 5.4 | 0.739 ± 0.039 | 0.80 | < 0.001* | 5.5 |