Table 1 Pulse sequence parameters used in the study
Dataset | Protocol name | Protocol type | TR (ms) | TE (ms) | Flip angle | No. Slices | Scan time (sec) | in-plane resolution (mm2) | Phase encoding direction | Slice thickness (mm) | Slice gap (mm) | FCa | SBD |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Initial comparing T1-weighted protocols | A | FLASH | 25 | 4.6 | 30 | 160 | 408 | 1.0x1.0 | Right-left | 2.0 | −1 | - | - |
B | MPRAGE | 9.8 | 4.6 | 8 | 120 | 279 | 1.16x1.1 | Right-left | 1.2 | 0 | - | - | |
C | MPRAGE | 7.6 | 3.5 | 8 | 160 | 614 | 1.0x1.0 | Anterior-posterior | 1.0 | 0 | - | - | |
D | MPRAGE | 7.6 | 3.5 | 8 | 160 | 614 | 1.0x1.0 | Anterior-posterior | 1.05 | 0 | - | - | |
E | MPRAGE | 9.8 | 4.6 | 8 | 120 | 279 | 1.16x1.1 | Right-left | 1.2 | 0 | - | - | |
F | MPRAGE | 7.1 | 3.3 | 8 | 145 | 557 | 1.0x1.0 | Anterior-posterior | 1.1 | 0 | - | - | |
Optimizing T1-weighted protocols | F | MPRAGE | 7.1 | 3.3 | 8 | 145 | 557 | 1.0x1.0 | Anterior-posterior | 1.1 | 0 | - | - |
F1 | MPRAGE | 7.1 | 3.3 | 8 | 145 | 557 | 1.0x1.0 | Anterior-posterior | 1.1 | 0 | - | ✓ | |
F2 | MPRAGE | 7.1 | 3.3 | 8 | 145 | 557 | 1.0x1.0 | Right-left | 1.1 | 0 | - | - | |
F3 | MPRAGE | 7.1 | 3.3 | 8 | 145 | 557 | 1.0x1.0 | Right-left | 1.1 | 0 | - | ✓ | |
C1 | MPRAGE | 9.5 | 5.3 | 8 | 160 | 614 | 1.0x1.0 | Anterior-posterior | 1.0 | 0 | ✓ | - | |
C2 | MPRAGE | 7.6 | 3.5 | 8 | 160 | 614 | 1.0x1.0 | Anterior-posterior | 1.0 | 0 | - | ✓ | |
C3 | MPRAGE | 10 | 5.6 | 8 | 160 | 614 | 1.0x1.0 | Right-left | 1.0 | 0 | ✓ | - |