Figure 3From: Tumour size measurement in a mouse model using high resolution MRI Tumour mass calculated from a) gauge block measurements, m GB , and b) 2D images, m 2D , vs. tumour mass measured after resection, m T . a) m GB vs. m T (n = 12). The correlation was strong when all tumour sizes were included (R2 = 1.0), but was lower in the assessment of small tumours only (inserted figure; m T <0.2 g, n = 9, m GB = 0.78m T + 0.00, R2 = 0.65). The corresponding correlation for m 3D-160 vs. m T for the same set of tumours was m 3D-160 = 0.93m T + 0.00, R2 = 1.00 (m T <0.2 g: m 3D-160 = 0.90m T + 0.00, R2 = 0.97). b) m 2D vs. m T (n = 15). The correlation was strong when all tumour sizes were included (R2 = 0.99), and persisted in the assessment of small tumours only (inserted figure, m T <0.2 g, n = 9, m 2D = 0.94m T + 0.00, R2 = 0.96). The corresponding correlation for m 3D-160 vs. m T for the same set of tumours was m 3D-160 = 0.93m T + 0.01, R2 = 1.0 (<0.2 g: m 3D-160 = 0.91m T + 0.00, R2 = 0.98).Back to article page