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Table 3 Serum levels of uric acid, creatinine, and blood urea nitrogen of four groups at different time points(P)

From: Renal interstitial fibrotic assessment using non-Gaussian diffusion kurtosis imaging in a rat model of hyperuricemia

Uric acid (mg/dL)

 

CON

HUA

AP

AP + EM

P

base

2.037 ± 0.162

1.960 ± 0.349

2.329 ± 0.353

2.077 ± 0.535

0.664

1d

2.000 ± 0.778

4.251 ± 0.585

4.153 ± .0271

4.067 ± 0.181

0.002*

5d

1.849 ± 0.407

5.781 ± 0.450

4.868 ± 0.421

4.715 ± 0.434

< 0.001*

9d

2.198 ± 0.492

6.042 ± 0.295

5.121 ± 0.368

5.008 ± 0.373

< 0.001*

Creatinine (μmol/L)

 

CON

HUA

AP

AP + EM

P

base

25.230 ± 2.561

25.953 ± 2.106

25.277 ± 2.608

28.293 ± 2.507

0.427

1d

26.297 ± 2.688

26.303 ± 1.778

27.093 ± 1.306

29.080 ± 1.284

0.286

5d

26.790 ± 2.483

25.330 ± 2.455

26.460 ± 4.500

28.207 ± 2.319

0.727

9d

28.117 ± 1.636

28.403 ± 3.766

27.330 ± 3.690

28.843 ± 1.917

0.932

Blood urea nitrogen (mmol/L)

 

CON

HUA

AP

AP + EM

P

base

4.377 ± 0.374

4.277 ± 0.230

4.770 ± 0.336

4.270 ± 0.336

0.265

1d

4.493 ± 0.726

4.173 ± 0.750

4.760 ± 0.344

5.027 ± 0.479

0.398

5d

5.083 ± 0.474

4.790 ± 0.322

4.903 ± 0.446

5.530 ± 0.707

0.358

9d

4.373 ± 0.211

4.590 ± 0.682

4.673 ± 0.771

5.4033 ± 0.873

0.344

  1. Bold characteristics and *, were generated from comparisons between four groups at each time point by using one-way ANOVA
  2. CON control, HUA hyperuricemia, AP allopurinol, AP + EM allopurinol + empagliflozin, base basement
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BMC Medical Imaging

ISSN: 1471-2342

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