Fig. 3

Patient 12 presented with NPC. On the WBS (a), there is an area of abnormal ^99mTc-MDP uptake seen in the left upper tibia, which may mimic bone metastasis. No additional area of abnormal ^99mTc-MDP uptake was identified on the remainder of the skeleton. Axial CT (b), SPECT (c), and hybrid SPECT/spiral CT imaging (d) depicted show increasing ^99mTc-MDP uptake corresponding to a sclerotic lesion with GGO localized in the left tibia. Based on the imaging finding which was suspicious for primary bone malignancy. A biopsy was subsequently performed and pathologic analysis confirmed the diagnosis of FD