The assessment of accessory mental foramen in a selected polish population: a CBCT study
- Ewa Zmysłowska-Polakowska†1,
- Mateusz Radwański†1,
- Michał Łęski1,
- Sławomir Ledzion1,
- Monika Łukomska-Szymańska2 and
- Michał Polguj3Email author
© The Author(s). 2017
Received: 14 November 2016
Accepted: 13 February 2017
Published: 20 February 2017
Accessory mental foramen (AMF) is a rare anatomical variation. When accessory mental foramen is present, the nerves and vessels that go through the mental foramen (MF) must follow alternative courses and special care must be taken during dental treatment planning. The purpose of this study was to evaluate the occurrence and the location of AMF in a selected Polish population using cone-beam computed tomography (CBCT).
Two hundred CBCT (105 males and 95 females) examinations were evaluated for the presence of AMFs. The location and side of AMFs were reported. The mean distance between MF and AMF was also calculated. The vertical size of MF on the side with and without AMF was measured. The obtained variables were statistically analyzed.
AMFs were observed in 7% of the patients. There was no statistically significant difference between the appearance of AMF and sex (p > 0.05). We found no significant difference in the vertical size of MF between individuals with and without AMFs (p < 0.05).
Twenty-eight AMFs (7%) were observed from 400 sides of 200 patients. AMFs occurred more often in males (18 AMFs) than in females (10 AMFs). Twenty AMFs (71.4%) were located anteriorly, and eight (28.6%) - posteriorly. Fifteen AMFs (53.6%) were on the right side and thirteen (46.4%) - on the left.
KeywordsAccessory mental foramen Cone-beam computed tomography CBCT Dental surgery Endodontics
The mental foramen (MF) is a bilateral opening in the mandible through which nerve endings such as the mental nerve, a branch of the inferior alveolar nerve and corresponding arteries and veins emerge [1–4]. Once the nerve leaves the MF, it branches to innervate the anterior teeth and neighboring structures. The blood vessels supply the soft tissues of the lower jaw [5, 6]. The position of the mental foramen is used as a reference point in the anesthetic technique such as the incisive/mental nerve block. In dental practice, the importance of this structure is mainly related to the positioning of dental implants and to other surgical procedures in this region, for example endodontic surgery. There are some reports on the anatomical variations of the MF such as the presence of accessory mental foramina (AMFs) [2, 5, 7–11]. When AMF is present, the nerves and vessels that go through the mental foramen must follow alternative courses and special care must be taken during dental treatment planning.
Accessory mental foramen has a different description in literature. Some authors described AMF as any additional foramina except the main MF [5, 12]. On the other hand, only those foramina that are integrated with mandibular canal are nominated as AMFs [13–15]. Conversely, the foramen which does not originate in the mandibular canal and its dimensions are relatively small is recognized as a nutrient foramen .
The presence of AMF can be evaluated with different methods including macroscopic investigations on dry skulls [14, 17, 18], plane radiographs (including periapical and panoramic views)  and computed tomography images (CT or CBCT) . The crucial benefit of cone-beam computed tomography (CBCT) is overcoming the limitations of conventional radiography by producing three-dimensional (3D) images that allow comprehensive evaluation of the anatomy of the chosen region . CBCT is an useful tool that provides detailed information on the structures of the maxillofacial complex, permitting the identification and the evaluation of anatomical variations [19, 20].
The purpose of this study was to evaluate the occurrence and location of the accessory mental foramen in a selected Polish population using CBCT.
This retrospective study consisted of 487 CBCTs obtained from 2011 to 2012 in the Radiology Department at the Central Teaching Hospital, Institute of Dentistry, of the Medical University of Lodz (Poland). Images were performed for different diagnostic reasons, such as bone absence for implant placement, assessment of tooth relationships with clinically relevant anatomical structures, dental surgery and diagnosis of radiolucent lesions. The CBCT scans were selected according to the following inclusion criteria: visibility of MF, no lesion observed in the apical area of premolars and MF, no bone resorption occurrence. Only images with availability of precise information about patient age and sex were selected. The exclusion criteria consist of CBCT images with large pathological lesions in mandible and bone fractures in region of examination. Also inadequate picture quality with artefacts caused by osteosynthesis plates/implants or patient movement during exposure were rejected. According to our inclusion and exclusion criteria, the final sample group included data from 200 patients (105 males and 95 females). This study has obtained a positive opinion of the Ethics Committee of Medical University of Lodz, Poland (No. RNN/322/15/KE).
Accessory mental foramen (AMF) in this cross-sectional study was defined as a buccal foramen smaller than the mental foramen and followed by the accessory branch of the mental canal before it exits from the mental foramen, regardless of its location.
There were 105 males (52.5%) and 95 females (47.5%) in the study group. The average age of the 200 patients who were included in this study was 54.57 years (range: 29 to 76 years, SD: 10.26 years). The mean age of the males was 54.49 years (range: 29 – 76 years, SD: 10.79), while the mean age of the females was 54.66 years (range: 39 – 75 years, SD: 9.72).
The distance between the AMF and the MF ranged from 0.64 to 6.5 mm with the mean of 2.86 mm (SD: 1.34 mm).
Vertical sizes of MF and the presence of AMFs
Vertical size of MF (mm)
MF on the side with AMF
p > 0.05
MF on the side without AMF
The presence of an AMF has been suggested to result from the branching of the mental nerve before it exits the mental foramen. Ignoring the presence of AMF may cause unexpected damage to the neurovascular bundles or lead to the failure of a mental nerve block.
According to Balcioglu and Kocaelli , the presence of AMF is a rather rare anatomical variation with the prevalence ranging from 1.4 to 10%. The differences may be explained by different imaging techniques and race. Panoramic radiography provides a flat image of the curved structure and is not as accurate as CBCT in the horizontal localization of objects. Their report also revealed that non-Caucasians have a higher prevalence of AMF than Caucasians . On the other hand, accessory mental foramen in comparison to very rare skeletal variations like double suprascapular foramen are a common anomaly .
The prevalence of AMF varies in different ethnic groups. The highest is reported in black and Maori males . Kalender et al.  observed AMF in 6.5% of a Turkish population, and prevalence of 6.68 and 7% were found in Greek  and Japanese  populations, respectively. In adult Sri Lankan  and Indian  populations, the prevalence of AMF was found to be 3.92 and 8.9%, respectively. In the present study, the AMFs were detected in 7% of the selected Polish population.
In our study, AMFs occurred more often in males (18 AMFs) than in females (10 AMFs). However, the difference was no statistically significant (p > 0,05). Other studies also confirmed that AMFs were more commonly found in males [14, 15]. Göregen et al.  in their study observed the same number of AMFs in males and females with no statistical differences between these groups.
The location of AMF is also important and can directly affect the treatment plan since it might interfere with performed procedures. Katakami et al.  in the study of 150 patients, observed the presence of 17 accessory mental foramina by CBCT with 59% of which being posteriorly located to the mental foramen. Another study conducted on 157 patients demonstrated the presence of 15 accessory mental foramina, nine of which posteriorly located . On the other hand, the study of 315 patients of a Turkish population revealed the occurrence of 22 AMFs, twelve of which (54,5%) anteriorly located . In the present study, twenty (71.4%) of twenty-eight AMFs were anteriorly located.
The next measured parameter was the distance between the mental foramen and the accessory mental foramen. Göregen et al.  reported that the distance ranged from 1.6 to 4.9 mm, with the mean of 2.54 mm (SD: 1.1 mm). In the studies of Naitoh et al.  and Kalender et al. , the mean value ranged from 4.5 to 9.6 mm, with the mean of 6.3 mm (SD: 1.5 mm) and from 1.3 to 15.4 mm, with the mean of 5.2 mm (SD: 4.4 mm), respectively. In the present study, the distance between the AMF and the MF ranged from 0.64 to 6.5 mm with the mean of 2.86 mm (SD: 1.34 mm)
The mean vertical size of the MF on the same side as the AMF was 3.21 mm (range: 1.74 – 5.82 mm, SD: 0.98), and that of MF on the sides without AMF was 3.26 mm (range: 1.12 – 7.02 mm, SD: 0.97 mm). The relationship between the mean vertical size of the MF and the presence of the AMF was not statistically significant (p > 0.05). Similar results were reported by Naitoh et al.  and Göregen et al. .
In 2013, Chen et al.  described a new method of improvement of computed tomography images. They used fast dictionary learning-based processing. This method brings encouraging improvements in abdomen low-dose computed tomography images with tumours. In 2014, Chen et al.  used novel image-domain algorithm called "artefact-suppressed dictionary learning". In this method, orientation and scale information on artefacts is exploited to train artefact atoms. These artefact atoms are then combined with tissue feature atoms to build three discriminative dictionaries. Authors provided qualitative and quantitative evaluations of this method on a large set of abdominal and mediastinal computed tomography investigation. In 2016, Chen et al.  described new technique of minimal path propagation with backtracking for curve-like structure extraction. They found that the information in the process of backtracking from reached points can be well utilized to improve the extraction performance.
Preoperative imaging study is important prior to any surgical or anaesthetic procedure in mental regio. AMF is a relevant anatomic structure, which should be considered in treatment plan of procedure performed in mandible (i.e. root resection of mandibular premolars or molars, osteotomy, mandibular rehabilitation after trauma, placement of dental implants). The detection of AMF has a direct influence on therapeutic success. In patients with AMF, accessory mental nerve and vessels may be present. The presence of accessory innervations may explain failures to achieve adequate levels of anaesthesia during surgical and routine dental procedures using conventional nerve block techniques. The detection of AMF can prevent nerve and vascular injury and reduce complications of dental treatment such as: paralysis, hemorrhage and post-operative pain.
In the present study, the occurrence of the accessory mental foramen in the study of the Polish population is similar to that described in Turkish, Greek and Japanese population. Awareness of anatomy and its variations are essential to ensure precise dental procedure execution. Moreover, it is crucial to better understand possible anatomical conditions that can promote neurosensory disturbance in treated area.
Accessory mental foramen
Cone-beam computed tomography
Department of Endodontics, 503/2-044-02/503-01.
Availability of data and materials
Please contact authors for data requests (Dr. Ewa Zmysłowska-Polakowska - email address: email@example.com or Dr. Mateusz Radwański - email address: firstname.lastname@example.org).
E Z-P: study design, data collection, data interpretation, manuscript preparation, figure preparation, fund collection; MR: study design, data collection, data interpretation, manuscript preparation, figure preparation, literature search; MŁ: data collection, manuscript preparation; SL: data collection, manuscript preparation, literature search; M Ł-Sz: manuscript preparation, fund collection; MP: study design, manuscript preparation. All authors read and approved the final manuscript.
The authors declare that they have no competing interests and no conflicts of interests to disclose.
Consent for publication
Ethics approval and consent to participate
The ethical approval for this study was obtained from the Ethics Committee of Medical University of Lodz, Poland (No. RNN/322/15/KE).
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Boopathi S, et al. Anthropometric analysis of the infraorbital foramen in a South Indian population. Singapore Med J. 2010;51(9):730–5.PubMedGoogle Scholar
- Concepcion M, Rankow HJ. Accessory branch of the mental nerve. J Endod. 2000;26(10):619–20.View ArticlePubMedGoogle Scholar
- Iwanaga J, et al. The clinical anatomy of accessory mental nerves and foramina. Clin Anat. 2015;28(7):848–56.View ArticlePubMedGoogle Scholar
- Iwanaga J, et al. Accessory mental foramina and nerves: application to periodontal, periapical, and implant surgery. Clin Anat. 2016;29(4):493–501.View ArticlePubMedGoogle Scholar
- Balcioglu HA, Kocaelli H. Accessory mental foramen. North Am J Med Sci. 2009;1(6):314–5.Google Scholar
- Roa I, Arriagada O. Anatomical variations of mandibular canal with clinical significance. Case report. Int J Morphol. 2015;33(3):971–4.View ArticleGoogle Scholar
- Al-Shayyab MH, et al. The mental foramen II: radiographic study of the superior-inferior position, appearance and accessory foramina in iraqi population. Int J Morphol. 2016;34(1):310–9.View ArticleGoogle Scholar
- Goregen M, et al. The assessment of accessory mental foramina using cone-beam computed tomography. Turk J Med Sci. 2013;43(3):479–83.Google Scholar
- Neves FS, et al. Lingual accessory mental foramen: a report of an extremely rare anatomical variation. J Oral Sci. 2010;52(3):501–3.View ArticlePubMedGoogle Scholar
- Patil S, Matsuda Y, Okano T. Accessory mandibular foramina: a CT study of 300 cases. Surg Radiol Anat. 2013;35(4):323–30.View ArticlePubMedGoogle Scholar
- Trikeriotis D, et al. Anterior mandible canal communications: a potential portal of entry for tumour spread. Dentomaxillofac Radiol. 2008;37(3):125–9.View ArticlePubMedGoogle Scholar
- Singh R, Srivastav AK. Study of position, shape, size and incidence of mental foramen and accessory mental foramen in indian adult human skulls. Int J Morphol. 2010;28(4):1141–6.View ArticleGoogle Scholar
- Katakami K, et al. Characteristics of accessory mental foramina observed on limited cone-beam computed tomography images. J Endod. 2008;34(12):1441–5.View ArticlePubMedGoogle Scholar
- Khojastepour L, et al. Location of mental foramen in a selected iranian population: a CBCT assessment. Iran Endod J. 2015;10(2):117–21.PubMedPubMed CentralGoogle Scholar
- Naitoh M, et al. Accessory mental foramen assessment using cone-beam computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(2):289–94.View ArticlePubMedGoogle Scholar
- Torres MGG, et al. Accessory mental foramen: a rare anatomical variation detected by cone-beam computed tomography. Imaging Sci Dent. 2015;45(1):61–5. doi:10.5624/isd.2015.45.1.61.View ArticlePubMedPubMed CentralGoogle Scholar
- Haktanir A, Ilgaz K, Turhan-Haktanir N. Evaluation of mental foramina in adult living crania with MDCT. Surg Radiol Anat. 2010;32(4):351–6.View ArticlePubMedGoogle Scholar
- Paraskevas G, Mavrodi A, Natsis K. Accessory mental foramen: an anatomical study on dry mandibles and review of the literature. Oral Maxillofac Surg. 2015;19(2):177–81.View ArticlePubMedGoogle Scholar
- Nozu Imada TS, et al. Accessory mental foramina: prevalence, position and diameter assessed by cone-beam computed tomography and digital panoramic radiographs. Clin Oral Implants Res. 2014;25(2):94–9.View ArticleGoogle Scholar
- Naitoh M, et al. Comparison between cone-beam and multislice computed tomography depicting mandibular neurovascular canal structures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(1):19–25.View ArticleGoogle Scholar
- Polguj M, Podgórski M, Jędrzejewski K, Topol M. The double suprascapular foramen: unique anatomical variation and the new hypothesis of its formation. Skeletal Radiol. 2012;41(12):1631–6.View ArticlePubMedPubMed CentralGoogle Scholar
- Kieser J, et al. Patterns of emergence of the human mental nerve. Arch Oral Biol. 2002;47(10):743–7.View ArticlePubMedGoogle Scholar
- Kalender A, Orhan K, Aksoy U. Evaluation of the mental foramen and accessory mental foramen in Turkish patients using cone-beam computed tomography images reconstructed from a volumetric rendering program. Clin Anat. 2012;25(5):584–92.View ArticlePubMedGoogle Scholar
- Zografos J, Mutzuri A. Incidence of double mental foramen in a sample of Greek population. Odontostomatol Proodos. 1989;43(6):521–3.PubMedGoogle Scholar
- Ilayperuma I, Nanayakkara G, Palahepitiya N. Morphometric analysis of the infraorbital foramen in adult Sri lankan skuls. Int J Morphol. 2010;28(3):777–82.View ArticleGoogle Scholar
- Sankar DK, Bhanu SP, Susan PJ. Morphometrical and morphological study of mental foramen in dry dentulous mandibles of south andhra population of india. Indian J Dent Res. 2011;22(4):542–6.View ArticlePubMedGoogle Scholar
- Chen Y, Yin X, Shi L, Shu H, Luo L, Coatrieux JL, Toumoulin C. Improving abdomen tumor low-dose CT images using a fast dictionary learning based processing. Phys Med Biol. 2013;58(16):5803–20.View ArticlePubMedGoogle Scholar
- Chen Y, Shi L, Feng Q, Yang J, Shu H, Luo L, Coatrieux JL, Chen W. Artifact suppressed dictionary learning for Low-dose CT image processing. IEEE Trans Med Imaging. 2014;33(12):2271–92.View ArticlePubMedGoogle Scholar
- Chen Y, Zhang Y, Yang J, Cao Q, Yang G, Chen J, Shu H, Luo L, Coatrieux JL, Feng Q. Curve-like structure extraction using minimal path propagation with backtracking. IEEE Trans Image Process. 2016;25(2):988–1003.View ArticlePubMedGoogle Scholar