Figure 5

vWF, Synaptophysin, human cell specific staining (anti β2 mitochondrial antibody) and staining for rat macrophages. Upper (first) panel: vWF staining showed significantly higher number of vWF positive cells in animals that received In-111 labeled hUTC. 2nd panel: Similarly synaptophysin staining also showed significantly increased expression in animals that received In-111 hUTC. 3rd panel: A few human specific β-mitochondria positive cells were observed in animals that received In-111 hUTC (black arrows) indicating presence of human cells. Lower (fourth) panel: Sections are from IBZ in animals that received In-111-oxine (left) and In-111-labeled hUTC (right). CD68 positive cells (green color, white arrows) are abundant in IBZ. However, a few human cells (Red color, yellow arrows) are seen in animals that received labeled cells. A few red colored spots are seen in both sections (green arrows), which do not correspond to any nucleus (DAPI positive) are probably artifacts.