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Table 1 Difference of ROI volumes between the automated and the manual protocol

From: Automated vs manual delineations of regions of interest- a comparison in commercially available perfusion MRI software

Program

Perfscape/Neuroscape

PMA

PMA with filtering *

Stroketool

Stroketool with filtering *

Median

Median

Median

Median

Median

IQR

IQR

IQR

IQR

IQR

Parameter

     

Tmax 4 s

25.80

123.68

64.91

122.89

37.50

12.8–66.1

75.2–206.8

27.3–138.1

75.6–176.5

14.9–75.3

Tmax 6 s

12.74

29.48

4.83

53.18

7.75

4.1–34.4

16.4–67.8

1.0–22.4

34.0–82.6

1.8–18.3

Tmax 8 s

8.05

23.16

2.68

31.78

1.67

2.6 - 28.1

13.5 – 55.4

0.4 – 15.8

16.1 – 50.1

0.2 – 6.5

MTT 5 s

186.78

35.12

11.59

129.35

58.74

151.4–248.5

17.8–87.8

3.4–44.1

82.5–225.7

21.8–130.5

MTT 6 s

154.40 114.8–207.0

16.76 8.4–49.0

4.34 0.9–18.4

80.18 49.1–143.6

26.51 8.0–63.7

MTT 8 s

94.24

7.36

0.77

33.82

6.07

55.0–143.3

3.8–17.4

0.3–3.9

20.9–57.6

1.6–18.8

CBF highest threshold

209.92

54.35

23.05

134.50

67.28

160.0–262.8

27.5–107.9

7.6–64.4

89.9–193.0

39.0–110.2

CBF medium threshold

151.93

36.14

10.51

87.28

35.27

97.6–212.2

18.6–65.9

3.7–36.5

59.4–134.0

18.1–61.7

CBF lowest threshold

63.66

23.40

4.33

53.95

12.73

 

39.6–119.4

13.3–39.3

1.4–15.3

37.2–83.0

6.6–28.4

  1. CBF indicates cerebral blood flow; MTT mean transit time; IQR interquartile range. All values are in ml. * Values indicate volumes after additional CSF filtering in SPM8.